Researcher

Yiyi Yan, MD, PhD

Mayo Clinic

Education:

-MD degree from Shanghai Second Medical University, Shanghai, China

-MS degree from University of Texas Graduate School of Biomedical Science, Houston, Texas

-PhD degree from University of Texas Graduate School of Biomedical Science, Houston, Texas

-Postdoctoral fellow in Cancer Genetics at MD Anderson Cancer Center, Houston, Texas

-Residency in Internal Medicine and Chief Residency at York Hospital, York, Pennsylvania

-Fellowship in Hematology-Medical Oncology at Mayo Clinic, Rochester, Minnesota

-Current K12 scholar in the Paul Calabresi Program in Clinical Translational Research, Mayo Clinic, Rochester, Minnesota

-Currently Senior Associate Consultant and Assistant Professor of Medicine and Oncology at Mayo Clinic, Rochester, Minnesota


Personal

Dr. Yan is from Shanghai, China.


Research Focus:

Dr. Yan’s clinical and research interests are in tumor immunology and immunotherapy of melanoma, especially in understanding the mechanisms of anti-tumor immune response to provide opportunities for integration of novel immunotherapies into more effective treatments.  Her goal is to discover predictive and prognostic biomarkers, and to develop treatment strategies with improved clinical outcomes. She has been closely collaborating with Drs. Haidong Dong and Svetomir Markovic’s laboratories at Mayo Clinic and identified new immunoregulatory effects of chemotherapy in metastatic melanoma patients in the setting of immunotherapy.  She was awarded the K12 grant in the Paul Calabresi Program in Clinical Translational Research for her project to understand the immunomodulatory effects of chemotherapy.  Dr. Yan’s current research focus is to understand the cellular and molecular mechanisms of chemo-immunotherapy combination.